Research programmes
ZELS
KCRI is a partner in Livestock, Livelihoods and Health, a multidisciplinary, international research programme exploring diseases that can be transmitted from wild or domesticated animals to people (zoonoses). The programme comprises three projects: SEEDS “Investigating the social, economic and environmental drivers of zoonoses in Tanzania”, HAZEL “Hazards associated with zoonotic enteric pathogens in emerging livestock meat pathways” and BRUCELOSSIS “Molecular epidemiology of brucelossis in northern Tanzania”. All the fieldwork is taking place in the Arusha, Kilimanjaro and Manyara regions, with laboratory work taking place in the specialised Zoonoses Laboratory at KCRI. The aim is to provide the evidence base to inform new strategies for zoonotic disease control and elimination in Tanzania, as well as elsewhere in East Africa. The programme is led by the University of Glasgow, UK, and is funded under the UK’s Zoonoses and Emerging Livestock Systems (ZELS) programme.
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PanACEA
The Pan-African Consortium for the Evaluation of Antituberculosis Antibiotics brings together a group of scientists from more that 14 countries with skills in clinical trials, pulmonology, mycobacteriology, pharmacokinetics, statistics and delivery of clinical service. The problem of tuberculosis is enormous and it is only by working together, clinicians and scientists, nations from the North and South, Universities, research institutions and health services that we will make progress. Thus, collaboration and partnership are central to the ethos of PanACEA. Thus, simply put the mission of PanACEA is: To shorten and simplify treatment of uncomplicated pulmonary TB, To increase the TB clinical trial capacity in Africa, To develop sustainable TB clinical trials network in Africa. Studies that were conducted in KCRI under PanACEA are Highrif-2, OEBA and MAMS.
PanBIOME
Awaiting Content
TanZamBo
KCRI is the training node for TanZamBo (Tanzania, Zambia, and Botswana) network forcapacity building in HIV prevention. Students from these countries come to KCRI to train at Masters level and return to their countries to carry out research and continue networking. In this way we promote South – South networking of future research leaders.
JMP
Awaiting content
EACCR
The East African Consortium for Clinical Research is an EDCTP funded project with the ultimate goal of integrating and synergizing efforts to strengthen research capacity, design, conduct, evaluate and communicate large multi-centre clinical trails under best international practices in this region, network amongst partners and improve-south and north-north collaborations and facilitate EDCTP’s vision of accelerating development of new drugs and tools to control HIV/AIDS, tuberculosis and malaria. EACCR Partners include Ethiopia, Germany, Kenya, The Netherlands, Sudan, Tanzania, Norway, Sweden, United Kingdom and Uganda.
MCDC
Malaria capacity development consortium is a consortium that aims at improving malaria research capacity in Africa through improving and strengthening the ability of African scientists from malaria endemic countries to undertake high quality research on malaria that will lead in the short to medium term to improved ways of treating or preventing this infection.
MCDC conducts a PhD fellowship programme for African scientists supported by the Wellcome Trust in five of the African Universities; among them being Kilimanjaro Christian Medical College, in Moshi, Tanzania,College of Medicine in Blantyre-Malawi, Kwame Nkrumah University of Science and Technology in Kumasi-Ghana, Makerere University in Kampala-Uganda and University of Dakar in Dakar-Senegal.
KCM College has four PhD candidates under this consortium. Students also receive support from the Liverpool School of Tropical medicine, The London School of Hygiene and Tropical Medicine or the University of Copenhagen. The consortium secretariat is based at the London School of Hygiene and Tropical Medicine (LSHTM).
THRiVE
Awaiting content
APRIORI
KCRI was in first instance founded as part of the APRIORI programme.African Poverty Related Infection Oriented Research Initiative aims at establishing a state-of-the art clinical research centre, and by involving African centres of excellence, strengthening south-south collaboration.
As such APRIORI would: Contribute to a new dimension of quality, Develop a new specialized training program (MSc, PhD, Clinical Trials), Establish an innovative and unique cooperation structure (north-south and south-south), Address the following scientific objectives (A) rationale vaccine development and down stream selection of candidates based on safety profile, analysis of immune response and efficacy and (B) in-depth pharmacological studies to optimise treatment protocols for TB.
The programme consist of the following 5 projects: Capacity building to establish KCRI, Phase I and II testing of malaria vaccines, Capacity building and establishment of clinical trail centre for testing new TB vaccines ( phase I/IIa) and TB drug interactions in the context of HIV in Africa, Concurrent treatment in TB and HIV co-infection, Development of drug regimens to shorten treatment for tuberculosis.