Background:

Melkersson-Rosenthal syndrome is a rare neurological disorder characterized by a triad of recurrent facial paralysis, fissured tongue, and persistent or recurring orofacial oedema, especially of the lower lip. The etiology is still not well understood, but genetic factors, allergic reactions and some infections have been linked to the disease. Currently, there is no causal treatment, but systemic steroids can be considered.

Case presentation:

We describe a 20-year-old female with Melkersson-Rosenthal syndrome who presented with the classical triad of lingua plicata, facial edema and facial paralysis.

Conclusion: Due to its rarity and the limited availability to follow-up care, MRS is likely not well known and therefore underdiagnosed in lower-resource regions.